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Controversy about pharmacological modulation of Nrf2 for cancer therapy

Conventional anticancer therapies such as radiotherapy and chemotherapies are associated with oxidative stress generating reactive oxygen species (ROS) and reactive aldehydes like 4-hydroxynonenal in cancer cells that govern them to die. The main mechanism activated due to exposure of the cell to th...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Milkovic, Lidija, Zarkovic, Neven, Saso, Luciano
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393166/
https://ncbi.nlm.nih.gov/pubmed/28411557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.013
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