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Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review
A major cell defense mechanism against oxidative and xenobiotic stress is mediated by the Nrf2/Keap1 signaling pathway. The Nrf2/Keap1 pathway regulates gene expression of many cytoprotective and detoxifying enzymes, thus playing a pivotal role in maintaining redox cellular homeostasis. Many disease...
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| Publicado no: | Drug Des Devel Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6161735/ https://ncbi.nlm.nih.gov/pubmed/30288023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S172612 |
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