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Expression of the Tpl2/Cot oncogene in human T-cell neoplasias
BACKGROUND: Tpl2/Cot oncogene has been identified in murine T-cell lymphomas as a target of MoMuLV insertion. Animal and tissue culture studies have shown that Tpl2/Cot is involved in interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) production by T-cells contributing to T-cell proliferation....
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC539294/ https://ncbi.nlm.nih.gov/pubmed/15575964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-34 |
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