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Expression of the Tpl2/Cot oncogene in human T-cell neoplasias

BACKGROUND: Tpl2/Cot oncogene has been identified in murine T-cell lymphomas as a target of MoMuLV insertion. Animal and tissue culture studies have shown that Tpl2/Cot is involved in interleukin-2 (IL-2) and tumor necrosis factor-α (TNF-α) production by T-cells contributing to T-cell proliferation....

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Detalhes bibliográficos
Main Authors: Christoforidou, Anna V, Papadaki, Helen A, Margioris, Andrew N, Eliopoulos, George D, Tsatsanis, Christos
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539294/
https://ncbi.nlm.nih.gov/pubmed/15575964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-3-34
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