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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines

Tpl-2 expression is induced within 30–60 min after ConA stimulation of rat splenocytes, suggesting that it may contribute to the induction of IL-2 during T cell activation. Herein we show that wild-type and carboxyl-terminally truncated (activated) Tpl-2 activate the nuclear factor of activated T ce...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Tsatsanis, Christos, Patriotis, Christos, Bear, Susan E., Tsichlis, Philip N.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19922/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9520452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.7.3827
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