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The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines

Tpl-2 expression is induced within 30–60 min after ConA stimulation of rat splenocytes, suggesting that it may contribute to the induction of IL-2 during T cell activation. Herein we show that wild-type and carboxyl-terminally truncated (activated) Tpl-2 activate the nuclear factor of activated T ce...

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Bibliografiske detaljer
Main Authors: Tsatsanis, Christos, Patriotis, Christos, Bear, Susan E., Tsichlis, Philip N.
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19922/
https://ncbi.nlm.nih.gov/pubmed/9520452
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