TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.

Despite its initial positive response to hormone ablation therapy, prostate cancers invariably recur in more aggressive, treatment resistant forms. The lack of our understanding of underlying genetic alterations for the transition from androgen-dependent (AD) to ADI prostate cancer growth hampers ou...

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Detalles Bibliográficos

Principais autores:	Joseph H Jeong, Ayesha Bhatia, Zsolt Toth, Soohwan Oh, Kyung-Soo Inn, Chun-Peng Liao, Pradip Roy-Burman, Jonathan Melamed, Gerhard A Coetzee, Jae U Jung
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Acceso en liña:	http://europepmc.org/articles/PMC3022761?pdf=render
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