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Glial fibrillary acidic protein exhibits altered turnover kinetics in a mouse model of alexander disease
Mutations in the astrocyte-specific intermediate filament glial fibrillary acidic protein (GFAP) lead to the rare and fatal disorder, Alexander disease (AxD). A prominent feature of the disease is aberrant accumulation of GFAP. It has been proposed that this accumulation occurs because of an increas...
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| Publicat a: | J Biol Chem |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392575/ https://ncbi.nlm.nih.gov/pubmed/28223355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772020 |
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