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Alteration of glial-neuronal metabolic interactions in a mouse model of Alexander disease
Alexander disease is a rare and usually fatal neurological disorder characterized by the abundant presence of protein aggregates in astrocytes. Most cases result from dominant missense de novo mutations in the gene encoding glial fibrillary acidic protein (GFAP), but how these mutations lead to aggr...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908901/ https://ncbi.nlm.nih.gov/pubmed/20544858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21003 |
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