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Alteration of glial-neuronal metabolic interactions in a mouse model of Alexander disease

Alexander disease is a rare and usually fatal neurological disorder characterized by the abundant presence of protein aggregates in astrocytes. Most cases result from dominant missense de novo mutations in the gene encoding glial fibrillary acidic protein (GFAP), but how these mutations lead to aggr...

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Detalhes bibliográficos
Main Authors: Meisingset, Tore Wergeland, Risa, Øystein, Brenner, Michael, Messing, Albee, Sonnewald, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908901/
https://ncbi.nlm.nih.gov/pubmed/20544858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21003
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