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Effective combination therapies for B cell lymphoma predicted by a virtual disease model

The complexity of cancer signaling networks limits the efficacy of most single agent treatments and brings about challenges in identifying effective combinatorial therapies. In this study, we used chronic active B cell receptor (BCR) signaling in diffuse large B cell lymphoma (DLBCL) as a model syst...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Du, Wei, Goldstein, Rebecca, Jiang, Yanwen, Aly, Omar, Cerchietti, Leandro, Melnick, Ari, Elemento, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392381/
https://ncbi.nlm.nih.gov/pubmed/28130226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-0476
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