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The Epigenetic basis of diffuse large B-cell lymphoma

The pathogenesis of DLBCL is strongly linked to perturbation of epigenetic mechanisms. The germinal center (GC) B-cells from which DLBCLs arise are prone to instability in their cytosine methylation patterns. DLBCLs inherit this epigenetic instability and display variable degrees of epigenetic heter...

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Bibliographic Details
Published in:Semin Hematol
Main Authors: Jiang, Yanwen, Melnick, Ari
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374125/
https://ncbi.nlm.nih.gov/pubmed/25805588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2015.01.003
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