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Genome-Wide Detection of Genes Targeted by Non-Ig Somatic Hypermutation in Lymphoma
The processes of somatic hypermutation (SHM) and class switch recombination introduced by activation-induced cytosine deaminase (AICDA) at the Immunoglobulin (Ig) loci are key steps for creating a pool of diversified antibodies in germinal center B cells (GCBs). Unfortunately, AICDA can also acciden...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395700/ https://ncbi.nlm.nih.gov/pubmed/22808135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040332 |
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