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Somatic hypermutation and B-cell lymphoma.

During the B-cell response to T-cell-dependent antigens, the B cells undergo a rapid proliferative phase in the germinal centre. This is accompanied by the introduction of mutations into the immunoglobulin (Ig) variable region (V) genes. The B cells are then selected according to the affinity of the...

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Bibliografiske detaljer
Main Authors: Dunn-Walters, D, Thiede, C, Alpen, B, Spencer, J
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087694/
https://ncbi.nlm.nih.gov/pubmed/11205334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2000.0751
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