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CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice
OBJECTIVES: The Ca/calmodulin-dependent protein kinase II (CaMKII), an arrhythmogenic molecule, is excessively activated in cardiac hypertrophy. Here, we investigated the effect of CaMKII inhibition in isoproterenol (ISO)-induced arrhythmias in hypertrophic mice. RESULTS: ISO induced multiple types...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392265/ https://ncbi.nlm.nih.gov/pubmed/28177919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15099 |
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