CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice

OBJECTIVES: The Ca/calmodulin-dependent protein kinase II (CaMKII), an arrhythmogenic molecule, is excessively activated in cardiac hypertrophy. Here, we investigated the effect of CaMKII inhibition in isoproterenol (ISO)-induced arrhythmias in hypertrophic mice. RESULTS: ISO induced multiple types...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Feng, Ying, Cheng, Jun, Wei, Baozhu, Wang, Yanggan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper: Pathology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392265/
https://ncbi.nlm.nih.gov/pubmed/28177919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15099
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