Mechanism of Vps4 hexamer function revealed by cryo-EM

Vps4 is a member of AAA(+) ATPase (adenosine triphosphatase associated with diverse cellular activities) that operates as an oligomer to disassemble ESCRT-III (endosomal sorting complex required for transport III) filaments, thereby catalyzing the final step in multiple ESCRT-dependent membrane remo...

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Publicat a:Sci Adv
Autors principals: Su, Min, Guo, Emily Z., Ding, Xinqiang, Li, Yan, Tarrasch, Jeffrey T., Brooks, Charles L., Xu, Zhaohui, Skiniotis, Georgios
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2017
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392032/
https://ncbi.nlm.nih.gov/pubmed/28439563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700325
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