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Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers

TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to char...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Inform
Hauptverfasser: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K, Zhang, Kun
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392013/
https://ncbi.nlm.nih.gov/pubmed/28469388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176935117691267
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