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Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers

TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to char...

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Detalhes bibliográficos
Publicado no:Cancer Inform
Main Authors: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K, Zhang, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392013/
https://ncbi.nlm.nih.gov/pubmed/28469388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176935117691267
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