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Significant Prognostic Features and Patterns of Somatic TP53 Mutations in Human Cancers

TP53 is the most frequently altered gene in human cancers. Numerous retrospective studies have related its mutation and abnormal p53 protein expression to poor patient survival. Nonetheless, the clinical significance of TP53 (p53) status has been a controversial issue. In this work, we aimed to char...

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Dettagli Bibliografici
Pubblicato in:Cancer Inform
Autori principali: Zhang, Wensheng, Edwards, Andrea, Flemington, Erik K, Zhang, Kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392013/
https://ncbi.nlm.nih.gov/pubmed/28469388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176935117691267
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