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Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors
The chemokine receptor CXCR4 is activated by its unique chemokine ligand CXCL12 and regulates many physiological and developmental processes such as hematopoietic cell trafficking. CXCR4 is also one of the main co-receptors for human immunodeficiency virus (HIV) entry. Dysfunction of the CXCL12/CXCR...
Enregistré dans:
| Publié dans: | PLoS One |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391968/ https://ncbi.nlm.nih.gov/pubmed/28410420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176057 |
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