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Signaling properties of the human chemokine receptors CXCR4 and CXCR7 by cellular electric impedance measurements

The chemokine receptor 4 (CXCR4) and 7 (CXCR7) are G-protein-coupled receptors involved in various diseases including human cancer. As such, they have become important targets for therapeutic intervention. Cell-based receptor assays, able to detect agents that modulate receptor activity, are of key...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Doijen, Jordi, Van Loy, Tom, De Haes, Wouter, Landuyt, Bart, Luyten, Walter, Schoofs, Liliane, Schols, Dominique
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612718/
https://ncbi.nlm.nih.gov/pubmed/28945785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0185354
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