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Modeling CBL activating mutations in vivo
In this issue of Blood, Nakata et al demonstrate that hematopoietic-specific expression of a mutation in the E3 ubiquitin ligase Casitas B cell lymphoma (CBL) results in a disorder that recapitulates the key features of human chronic myelomonocytic leukemia (CMML).(1) One of the challenges currently...
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Publicado no: | Blood |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391629/ https://ncbi.nlm.nih.gov/pubmed/28408421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-03-770222 |
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