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The mutational landscape of paroxysmal nocturnal hemoglobinuria revealed: new insights into clonal dominance
Paroxysmal nocturnal hemoglobinuria (PNH) is a disorder of hematopoietic stem cells that has largely been considered a monogenic disorder due to acquisition of mutations in the gene encoding PIGA, which is required for glycosylphosphatidylinositol (GPI) anchor biosynthesis. In this issue of the JCI,...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4191026/ https://ncbi.nlm.nih.gov/pubmed/25244089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77984 |
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