Clonal Cell Proliferation in Paroxysmal Nocturnal Hemoglobinuria: Evaluation of PIGA Mutations and T-cell Receptor Clonality

BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired pluripotent hematopoietic stem cell disorder associated with an increase in the number of glycosyl-phosphatidyl inositol (GPI)-deficient blood cells. We investigated PNH clonal proliferation in the three cell lineages—granulocytes,...

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Detalhes bibliográficos
Publicado no:Ann Lab Med
Main Authors: Park, Joonhong, Kim, Myungshin, Kim, Yonggoo, Han, Kyungja, Chung, Nack-Gyun, Cho, Bin, Lee, Sung-Eun, Lee, Jong Wook
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Laboratory Medicine 2019
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502953/
https://ncbi.nlm.nih.gov/pubmed/31037862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2019.39.5.438
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