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JAK-STAT Signaling Pathways and Inhibitors Affect Reversion of Envelope-Mutated HIV-1
HIV can spread by both cell-free and cell-to-cell transmission. Here, we show that many of the amino acid changes in Env that are close to the CD4 binding pocket can affect HIV replication. We generated a number of mutant viruses that were unable to infect T cells as cell-free viruses but were never...
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| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391463/ https://ncbi.nlm.nih.gov/pubmed/28202754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00075-17 |
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