JAK/STAT Pathway Mutations in T-ALL, Including the STAT5B N642H Mutation, are Sensitive to JAK1/JAK3 Inhibitors

Lignende værker

• Mutant JAK3 signaling is increased by loss of wild-type JAK3 or by acquisition of secondary JAK3 mutations in T-ALL
  af: Degryse, Sandrine, et al.
  Udgivet: (2018)
• MOLECULAR PATHWAYS: JAK/STAT PATHWAY: MUTATIONS, INHIBITORS, AND RESISTANCE
  af: Quintás-Cardama, Alfonso, et al.
  Udgivet: (2013)
• Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma
  af: Yang, Shuqun, et al.
  Udgivet: (2015)
• STAT5B(N642H) is a driver mutation for T cell neoplasia
  af: Pham, Ha Thi Thanh, et al.
  Udgivet: (2017)
• Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia
  af: Cross, Nicholas C. P., et al.
  Udgivet: (2018)