Core engagement with β-arrestin is dispensable for agonist-induced vasopressin receptor endocytosis and ERK activation

G protein–coupled receptors (GPCRs) exhibit highly conserved activation and signaling mechanisms by which agonist stimulation leads to coupling of heterotrimeric G proteins and generation of second messenger response. This is followed by receptor phosphorylation, primarily in the carboxyl terminus b...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Kumari, Punita, Srivastava, Ashish, Ghosh, Eshan, Ranjan, Ravi, Dogra, Shalini, Yadav, Prem N., Shukla, Arun K.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391177/
https://ncbi.nlm.nih.gov/pubmed/28228552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-12-0818
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