Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection

Human cytomegalovirus (CMV) infection is a substantial cause of morbidity and mortality in immunocompromised hosts and globally is one of the most important congenital infections. The nucleoside analogue ganciclovir (GCV), which requires initial phosphorylation by the viral UL97 kinase, is the mains...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Rose, Jessica, Emery, Vincent C., Kumar, Deepali, Asberg, Anders, Hartmann, Anders, Jardine, Alan G., Bignamini, Angelo A., Humar, Atul, Neumann, Avidan U.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391089/
https://ncbi.nlm.nih.gov/pubmed/28406982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006299
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