Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection

Human cytomegalovirus (CMV) infection is a substantial cause of morbidity and mortality in immunocompromised hosts and globally is one of the most important congenital infections. The nucleoside analogue ganciclovir (GCV), which requires initial phosphorylation by the viral UL97 kinase, is the mains...

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Bibliografische gegevens
Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Rose, Jessica, Emery, Vincent C., Kumar, Deepali, Asberg, Anders, Hartmann, Anders, Jardine, Alan G., Bignamini, Angelo A., Humar, Atul, Neumann, Avidan U.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391089/
https://ncbi.nlm.nih.gov/pubmed/28406982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006299
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