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Wnt Signaling and Colorectal Cancer

The WNT signaling pathway is a critical mediator of tissue homeostasis and repair, and frequently co-opted during tumor development. Almost all colorectal cancers (CRC) demonstrate hyperactivation of the WNT pathway, which in many cases is believed to be the initiating and driving event. In this sho...

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Bibliographic Details
Published in:Curr Colorectal Cancer Rep
Main Authors: Schatoff, Emma M., Leach, Benjamin I., Dow, Lukas E.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391049/
https://ncbi.nlm.nih.gov/pubmed/28413363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11888-017-0354-9
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