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R-Spondin chromosome rearrangements drive Wnt-dependent tumour initiation and maintenance in the intestine
Defining the genetic drivers of cancer progression is a key in understanding disease biology and developing effective targeted therapies. Chromosome rearrangements are a common feature of human malignancies, but whether they represent bona fide cancer drivers and therapeutically actionable targets,...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5508203/ https://ncbi.nlm.nih.gov/pubmed/28695896 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15945 |
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