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Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance

For over four decades structural biology has been used to understand the mechanisms of disease, and structure-guided approaches have demonstrated clearly that they can contribute to many aspects of early drug discovery, both computationally and experimentally. Structure can also inform our understan...

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Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Pandurangan, Arun Prasad, Ascher, David B., Thomas, Sherine E., Blundell, Tom L.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390495/
https://ncbi.nlm.nih.gov/pubmed/28408471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160422
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