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Genomes, structural biology and drug discovery: combating the impacts of mutations in genetic disease and antibiotic resistance

For over four decades structural biology has been used to understand the mechanisms of disease, and structure-guided approaches have demonstrated clearly that they can contribute to many aspects of early drug discovery, both computationally and experimentally. Structure can also inform our understan...

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Dettagli Bibliografici
Pubblicato in:Biochem Soc Trans
Autori principali: Pandurangan, Arun Prasad, Ascher, David B., Thomas, Sherine E., Blundell, Tom L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390495/
https://ncbi.nlm.nih.gov/pubmed/28408471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160422
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