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Segmentum: a tool for copy number analysis of cancer genomes
BACKGROUND: Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes. Whole genome sequencing enables detailed characterization of such aberrations. However, due to the limitations of current high throughput sequencing technologies, thi...
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Publié dans: | BMC Bioinformatics |
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Auteurs principaux: | , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2017
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5390478/ https://ncbi.nlm.nih.gov/pubmed/28407731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1626-8 |
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