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Segmentum: a tool for copy number analysis of cancer genomes

BACKGROUND: Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes. Whole genome sequencing enables detailed characterization of such aberrations. However, due to the limitations of current high throughput sequencing technologies, thi...

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Détails bibliographiques
Publié dans:BMC Bioinformatics
Auteurs principaux: Afyounian, Ebrahim, Annala, Matti, Nykter, Matti
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390478/
https://ncbi.nlm.nih.gov/pubmed/28407731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1626-8
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