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Segmentum: a tool for copy number analysis of cancer genomes

BACKGROUND: Somatic alterations, including loss of heterozygosity, can affect the expression of oncogenes and tumor suppressor genes. Whole genome sequencing enables detailed characterization of such aberrations. However, due to the limitations of current high throughput sequencing technologies, thi...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Afyounian, Ebrahim, Annala, Matti, Nykter, Matti
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390478/
https://ncbi.nlm.nih.gov/pubmed/28407731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1626-8
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