ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

Cancer cells are frequently confronted with metabolic stress in tumor microenvironments due to their rapid growth and limited nutrient supply. Metabolic stress induces cell death through ROS-induced apoptosis. However, cancer cells can adapt to it by altering the metabolic pathways. AMPK and AKT are...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Principais autores: Zhao, Yang, Hu, Xingbin, Liu, Yajing, Dong, Shumin, Wen, Zhaowei, He, Wanming, Zhang, Shuyi, Huang, Qiong, Shi, Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390360/
https://ncbi.nlm.nih.gov/pubmed/28407774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0648-1
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