ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway

Cancer cells are frequently confronted with metabolic stress in tumor microenvironments due to their rapid growth and limited nutrient supply. Metabolic stress induces cell death through ROS-induced apoptosis. However, cancer cells can adapt to it by altering the metabolic pathways. AMPK and AKT are...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Zhao, Yang, Hu, Xingbin, Liu, Yajing, Dong, Shumin, Wen, Zhaowei, He, Wanming, Zhang, Shuyi, Huang, Qiong, Shi, Min
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390360/
https://ncbi.nlm.nih.gov/pubmed/28407774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0648-1
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