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Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination

Regulation of hormonal, insulin/IGF-1 (Ins/IGF-1) signaling activities, and pathways of the intrinsic generation of reactive oxygen species (ROS) play a role in aging and longevity determination. In this review we discuss the cross-talk between these pathways as mechanisms of signaling that may be i...

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Hlavní autor: Papaconstantinou, John
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873688/
https://ncbi.nlm.nih.gov/pubmed/19103250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.11.025
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