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Insulin/IGF-1 and ROS signaling pathway cross-talk in aging and longevity determination
Regulation of hormonal, insulin/IGF-1 (Ins/IGF-1) signaling activities, and pathways of the intrinsic generation of reactive oxygen species (ROS) play a role in aging and longevity determination. In this review we discuss the cross-talk between these pathways as mechanisms of signaling that may be i...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873688/ https://ncbi.nlm.nih.gov/pubmed/19103250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.11.025 |
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