Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

The insulin/IGF1 signaling pathways affect lifespan in several model organisms, including worms, flies and mice. To investigate whether common genetic variation in this pathway influences lifespan in humans, we genotyped 291 common variants in 30 genes encoding proteins in the insulin/IGF1 signaling...

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Autors principals: Pawlikowska, Ludmila, Hu, Donglei, Huntsman, Scott, Sung, Andrew, Chu, Catherine, Chen, Justin, Joyner, Alex, Schork, Nicholas J., Hsueh, Wen-Chi, Reiner, Alexander P., Psaty, Bruce M., Atzmon, Gil, Barzilai, Nir, Cummings, Steven R., Browner, Warren S., Kwok, Pui-Yan, Ziv, Elad
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652804/
https://ncbi.nlm.nih.gov/pubmed/19489743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00493.x
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