Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity

The insulin/IGF1 signaling pathways affect lifespan in several model organisms, including worms, flies and mice. To investigate whether common genetic variation in this pathway influences lifespan in humans, we genotyped 291 common variants in 30 genes encoding proteins in the insulin/IGF1 signaling...

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Detalhes bibliográficos
Main Authors: Pawlikowska, Ludmila, Hu, Donglei, Huntsman, Scott, Sung, Andrew, Chu, Catherine, Chen, Justin, Joyner, Alex, Schork, Nicholas J., Hsueh, Wen-Chi, Reiner, Alexander P., Psaty, Bruce M., Atzmon, Gil, Barzilai, Nir, Cummings, Steven R., Browner, Warren S., Kwok, Pui-Yan, Ziv, Elad
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3652804/
https://ncbi.nlm.nih.gov/pubmed/19489743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2009.00493.x
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