The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

BACKGROUND: Metabolic plasticity has been increasingly thought to be a determinant of tumor growth and metastasis. MACC1, a transcriptional regulator of MET, was recognized as an oncogene in gastric cancer (GC); however, its transcriptional or post-translational regulation was not clear. We previous...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Zhao, Yang, Liu, Yajing, Lin, Li, Huang, Qiong, He, Wanming, Zhang, Shuyi, Dong, Shumin, Wen, Zhaowei, Rao, Jinjun, Liao, Wangjun, Shi, Min
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5838949/
https://ncbi.nlm.nih.gov/pubmed/29510730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0820-2
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