The lncRNA MACC1-AS1 promotes gastric cancer cell metabolic plasticity via AMPK/Lin28 mediated mRNA stability of MACC1

Abstract Background Metabolic plasticity has been increasingly thought to be a determinant of tumor growth and metastasis. MACC1, a transcriptional regulator of MET, was recognized as an oncogene in gastric cancer (GC); however, its transcriptional or post-translational regulation was not clear. We...

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Detalhes bibliográficos
Main Authors: Yang Zhao, Yajing Liu, Li Lin, Qiong Huang, Wanming He, Shuyi Zhang, Shumin Dong, Zhaowei Wen, Jinjun Rao, Wangjun Liao, Min Shi
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-03-01
Colecção:Molecular Cancer
Assuntos:
MACC1-AS1
MACC1
Long non-coding RNA
Gastric cancer
Metabolic plasticity
mRNA stability
Acesso em linha:http://link.springer.com/article/10.1186/s12943-018-0820-2
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