The trans-Sialidase from Trypanosoma cruzi Induces Thrombocytopenia during Acute Chagas' Disease by Reducing the Platelet Sialic Acid Contents

Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease. The parasite sheds trans-sialidase, an enzyme able to mobilize the sialyl residues on cell surfaces, which is distributed in blood and...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Tribulatti, María Virginia, Mucci, Juan, Van Rooijen, Nico, Leguizamón, María Susana, Campetella, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2005
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC538983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15618155/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.73.1.201-207.2005
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