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Thymocyte depletion in Trypanosoma cruzi infection is mediated by trans-sialidase-induced apoptosis on nurse cells complex

Trypanosoma cruzi, the causative agent of Chagas' disease, induces transient thymic aplasia early after infection—a phenomenon that stills lacks a molecular explanation. The parasite sheds an enzyme known as trans-sialidase (TS), which is able to direct transfer-sialyl residues among macromolec...

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Detalhes bibliográficos
Main Authors: Mucci, Juan, Hidalgo, Alejandra, Mocetti, Esteban, Argibay, Pablo F., Leguizamón, M. Susana, Campetella, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122620/
https://ncbi.nlm.nih.gov/pubmed/11891302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.052496399
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