Inactive trans-Sialidase Expression in iTS-null Trypanosoma cruzi Generates Virulent Trypomastigotes

Disclosing virulence factors from pathogens is required to better understand the pathogenic mechanisms involved in their interaction with the host. In the case of Trypanosoma cruzi several molecules are associated with virulence. Among them, the trans-sialidase (TS) has arisen as one of particular r...

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Bibliografiske detaljer
Udgivet i:Front Cell Infect Microbiol
Main Authors: Pascuale, Carla A., Burgos, Juan M., Postan, Miriam, Lantos, Andrés B., Bertelli, Adriano, Campetella, Oscar, Leguizamón, M. Susana
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5632715/
https://ncbi.nlm.nih.gov/pubmed/29046868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00430
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