The trans-Sialidase from Trypanosoma cruzi Induces Thrombocytopenia during Acute Chagas' Disease by Reducing the Platelet Sialic Acid Contents

Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease. The parasite sheds trans-sialidase, an enzyme able to mobilize the sialyl residues on cell surfaces, which is distributed in blood and...

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Detalhes bibliográficos
Main Authors: Tribulatti, María Virginia, Mucci, Juan, Van Rooijen, Nico, Leguizamón, María Susana, Campetella, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538983/
https://ncbi.nlm.nih.gov/pubmed/15618155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.201-207.2005
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