Trypanosoma cruzi trans-Sialidase Prevents Elicitation of Th1 Cell Response via Interleukin 10 and Downregulates Th1 Effector Cells

The trans-sialidases (TSs) from Trypanosoma cruzi, the agent of Chagas disease, are virulence factors shed to the bloodstream that induce strong alterations in the immune system. Here, we report that both enzymatically active TS (aTS) and its lectinlike isoform (iTS) disturb CD4 T cell physiology, i...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Ruiz Díaz, Pablo, Mucci, Juan, Meira, María Ana, Bogliotti, Yanina, Musikant, Daniel, Leguizamón, María Susana, Campetella, Oscar
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399057/
https://ncbi.nlm.nih.gov/pubmed/25754197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00031-15
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi