Phosphoglycerate kinase 1 phosphorylates Beclin1 to induce autophagy

Autophagy is crucial for maintaining cell homeostasis. However, the precise mechanism underlying autophagy initiation remains to be defined. Here, we demonstrate that glutamine deprivation and hypoxia result in inhibition of mTOR-mediated acetyl-transferase ARD1 S228 phosphorylation, leading to ARD1...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Qian, Xu, Li, Xinjian, Cai, Qingsong, Zhang, Chuanbao, Jiang, Yuhui, Lee, Jong-Ho, Hawke, David, Wang, Yugang, Xia, Yan, Zheng, Yanhua, Jiang, Bing-Hua, Liu, David X., Jiang, Tao, Lu, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389741/
https://ncbi.nlm.nih.gov/pubmed/28238651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.027
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados