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PKM2 phosphorylates MLC2 and regulates cytokinesis of tumor cells
Pyruvate kinase M2 (PKM2) is expressed at high levels during embryonic development and tumor progression and is important for cell growth. However, it is not known whether it directly controls cell division. Here, we found that Aurora B phosphorylates PKM2, but not PKM1, at T45; this phosphorylation...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259466/ https://ncbi.nlm.nih.gov/pubmed/25412762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6566 |
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