FACT is a sensor of DNA torsional stress in eukaryotic cells

Transitions of B-DNA to alternative DNA structures (ADS) can be triggered by negative torsional strain, which occurs during replication and transcription, and may lead to genomic instability. However, how ADS are recognized in cells is unclear. We found that the binding of candidate anticancer drug,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Safina, Alfiya, Cheney, Peter, Pal, Mahadeb, Brodsky, Leonid, Ivanov, Alexander, Kirsanov, Kirill, Lesovaya, Ekaterina, Naberezhnov, Denis, Nesher, Elimelech, Koman, Igor, Wang, Dan, Wang, Jianming, Yakubovskaya, Marianna, Winkler, Duane, Gurova, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389579/
https://ncbi.nlm.nih.gov/pubmed/28082391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1366
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados