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A Mutation in the sap Operon Attenuates Survival of Nontypeable Haemophilus influenzae in a Chinchilla Model of Otitis Media

Bacteria have evolved strategies to resist killing by antimicrobial peptides (APs), important effectors of innate immunity. The sap (sensitivity to antimicrobial peptides) operon confers resistance to AP-mediated killing of Salmonella. We have recently shown that sapA gene expression is upregulated...

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Autori principali: Mason, Kevin M., Munson, Robert S., Bakaletz, Lauren O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC538956/
https://ncbi.nlm.nih.gov/pubmed/15618200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.599-608.2005
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